$40
for 4.5-Hours
Cooperativity and
Michaelis-Menton Kinetics
Review Session Details
- Kozlowski: Lectures W7 and W8A
- Boddy: Quiz 4
- Protein-Ligand binding (i.e., Kd)
- Saturation/Binding curves
- Cooperativity and Hill plots
- Sequential vs. Symmetry models
- Cooperativity of oxygen-hemoglobin transport
- Enzyme catalysisand free energy
- Steady-state approximation
- Michaelis-Menten enzyme kinetics (i.e., Km and Vmax)
- Michaelis-Menten equation and plots
- Lineweaver-burke plots (double reciprocal of Michaelis-Menten graph)
- KM, Kd, kcat, kcat/KM
- Review Session will include problem solving from past Midterm questions.
- All registered students will receive a "Midterm Package #4" that includes multiple Midterms/Quizes related to the above topics from previous years given by uOttawa Professors.
BCH2333/2733: Protein Binding and Michaelis-Menten Kinetics
$40.00
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$40
for 4.5-Hours
Enzyme Catalysis
and Inhibition
Review Session Details
- Kozlowski: Lectures W8B, W9A and W10A
- Boddy: Quiz 4 and 5
- Types of reversible inhibitors (i.e., alpha and Ki)
- Applying Line-weaver Burke plot for reversible inhibitors
- Types of irreversible inhibitors
- Types of enzyme catalysis:
- induced fit
- covalent catalysis
- acid-base catalysis
- catalysis by approximation
- metal-ion catalysis
- Identifying enzyme catalysis
- Cofactors and coenzymes
- Allosteric binding (i.e., Aspartate transcarbamoylase, ATCase)
- Enzyme regulations: isozymes, reversible covalent modification, proteolytic cleavage and transcriptional control
- Review Session will include problem solving from past Midterm questions.
- All registered students will receive a "Midterm Package #5" that includes multiple Midterms/Quizes related to the above topics from previous years given by uOttawa Professors.
BCH2333/2733: Enzyme Catalysis, Regulation and Inhibition
$40.00
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