BCH2333/2733: Enzyme Inhibition, Catalysis and Regulation

BCH2333/2733: Enzyme Inhibition, Catalysis and Regulation

Review Session Details
  • Kozlowski: Lectures W8B, W9A and W10A
  • Boddy: Quiz 4 and 5
  • Types of reversible inhibitors (i.e., alpha and Ki)
  • Applying Line-weaver Burke plot for reversible inhibitors¬†
  • Types of irreversible inhibitors
  • Types of enzyme catalysis:
    • induced fit
    • covalent catalysis
    • acid-base catalysis
    • catalysis by approximation
    • metal-ion catalysis
  • Identifying enzyme catalysis
  • Cofactors and coenzymes
  • Allosteric binding (i.e., Aspartate transcarbamoylase, ATCase)
  • Enzyme regulations: isozymes, reversible covalent modification, proteolytic cleavage and transcriptional control
  • Review Session will include problem solving from past Midterm questions.
  • All registered students will receive a "Midterm Package #5" that includes multiple Midterms/Quizes related to the above topics from previous years given by uOttawa Professors.