BCH2333/2733: Peptide, Protein Structure and Folding

BCH2333/2733: Peptide, Protein Structure and Folding

Review Session Details
  • Review amino acid side chain properties (i.e. pKa, charges, stereochemistry, trans/cis amide bonds)
  • Understand the 3 main dihedral angles regulating secondary structure (phi, psi and omega)
  • Apply dihedral angles to Ramachandran plot
  • Relate secondary structures to Ramachandran plot
  • Properties of helices (i.e. residues per turn, pitch, H-bonding, simple calculations, drawing helical wheel)
  • Properties of Beta-sheets (i.e. length per residue, H-bonding, types of turns, simple calculations)
  • Domains vs. motifs
  • How to identify type of quaternary structure (i.e. C2, C3, D2, D3 etc.)
  • Thermodynamics involved for protein folding
  • Understand what facilitates folding of proteins
  • All registered students will receive a "Midterm Package" that includes multiple Midterms/Quiz from previous years given by uOttawa Professors.