Review Session Details
- Review amino acid side chain properties (i.e. pKa, charges, stereochemistry, trans/cis amide bonds)
- Understand the 3 main dihedral angles regulating secondary structure (phi, psi and omega)
- Apply dihedral angles to Ramachandran plot
- Relate secondary structures to Ramachandran plot
- Properties of helices (i.e. residues per turn, pitch, H-bonding, simple calculations, drawing helical wheel)
- Properties of Beta-sheets (i.e. length per residue, H-bonding, types of turns, simple calculations)
- Domains vs. motifs
- How to identify type of quaternary structure (i.e. C2, C3, D2, D3 etc.)
- Thermodynamics involved for protein folding
- Understand what facilitates folding of proteins
